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2011 Aug;61(2):34457

Furthermore, factors such as innate immune responses, coagulopathy, the modulation of the anti-inflammatory/pro-inflammatory equilibrium, and immunosuppression, collectively play a role in the onset and progression of septic shock, potentially leading to organ dysfunction [98]

The interferons (IFN) The hypothesis that IFNs have an important role in SLE pathogenesis is supported by plethora of findings both in humans and animals